What Do You Mean By Non-steroidal Anti-inflammatory Drugs (NSAID)?
Non-steroidal Anti-inflammatory Drugs (NSAIDs) are also known as anti-inflammatories, which are a group of medications prescribed for pain management and inflammation, and these medicines have several active ingredients. The inflammation would mean swelling and redness which are associated with a certain type of arthritis, e.g., rheumatoid arthritis and other musculoskeletal disorders. NSAIDs are also used for the treatment of non-inflammatory conditions such as period pain, migraine, postoperative pain, and to reduce fever. This drug class provide analgesic and antipyretic effects, and when given in higher doses, anti-inflammatory effects. The term non-steroidal differentiates these drugs from steroids, which between a wide variants of other effects, have a similar anti-inflammatory and eicosanoid-depressing action. NSAID was first used in 1960, and the specific term was given so that it can distant new drugs from steroid related iatrogenic tragedies. A few common NSAIDs are aspirin, ibuprofen, i.e., Nurofen and diclofenac (Voltaren). Some of the other drugs include naproxen (Naprogesic), mefenamic acid, sethyl salicylate, piroxicam, ketoprofen and benzydamine. NSAIDs are present on their own and/or in combination with other active ingredients, such as codeine. These drugs also help in alleviating pain such as a simple headache, or any bone or muscle injury pain. Aspirin, in low dosages, as an NSAID along with blood thinning properties is used to reduce the risk of heart attack and stroke in high-risk patients.
Risks associated with using NSAIDs:
There are certain kinds of risks associated with all pain relievers; therefore, NSAIDs must be used with more precaution, particularly by individuals who are above 65 years of age, those who have probability of having heart or stomach problems, and asthma. NSAIDs are more potential than paracetamol to lead to any kind of side effects, specifically for people with some conditions which include the following:
- Chronic pain
- High blood pressure
- Heart failure
- Arthritis pain
- Inflammatory bowel disease (IBD)
- Impaired kidney function
- Impaired liver function
- More than 65 years of age
A study done conducted on the efficiency and probability of Non-steroidal Anti-inflammatory Drugs (NSAID) market states a few common side effects of these drugs – headache, diarrhoea, salt and fluid retention, dizziness, high blood pressure, and raised liver enzymes (detected by a blood test)
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